On this site, you will find our most recent studies and publications.
If you have any questions concerning the literature or if you would like to receive a printed copy of one of the papers, please feel free to get in contact with us.



Published in the year: 2017
Authors:
Schott D, Pizon M, Pachmann U, Pachmann K.
Title:
Sensitive detection of PD-L1 expression on circulatinge epithelial tumor cells (CETC) could be a potential biomarker to select patients for treatment with PD-1/PD-L1 inhibitors in early and metastatic solid tumors.
Published in Medium:
DOI:doi.org/10.18632/oncotarget.20346
Published in the year: 2017
Authors:
Schott D, Pizon M, Schuster S, Pachmann K.
Title:
Häufigkeit und Relevanz von PD-L1/2 auf zirkulierenden Tumorzellen in der Immuntherapie bei Brustkrebspatientinnen.
Published in Medium:
Gyne 2017, 2:26-28
Published in the year: 2016
Authors:
Schott D, Pizon M, Pachmann U, Pachmann K.
Title:
Comparison of phenotype and gene expression analysis of circulating epithelial tumor cells (CETCs) and tumorspheres in colorectal cancer patients.
Published in Medium:
Oncol Res Treat 2016, 39(suppl 2): 272 #P897
Published in the year: 2016
Authors:
Pizon M, Schott D, Pachmann U, Pachmann K.
Title:
The number of tumorspheres cultured from CETCs in breast cancer patients is directly related to stage of disease and administration of chemotherapy.
Published in Medium:
Ann Oncol 2016, 27(suppl 6): p534, #1545P
Published in the year: 2016
Authors:
Regina Willecke-Hochmuth, Katharina Pachmann, Joachim Drevs
Title:
Treatment of advanced solid tumours with NSAIDs: Correlation of quantitative monitoring of circulating tumour cells and positron emission tomography‑computed tomography imaging
Published in Medium:
ONCOLOGY LETTERS 12: 1711-1716, 2016
Published in the year: 2016
Authors:
Pizon M, Schott D, Pachmann K, Pachmann U.
Title:
The number of tumorspheres cultured from peripheral blood is a predictor for presence of metastasis in patients with breast cancer.
Published in Medium:
Oncotarget, Advance Publications 2016, doi:
Published in the year: 2016
Authors:
Schuster S, Pachmann K.
Title:
Zirkulierende epitheliale Tumorzellen: Echtzeitkontrolle in der adjuvanten Krebstherapie, der Erhaltungstherapie und Langzeitüberwachung.
Published in Medium:
DZKF 2016, 1:46-50
Published in the year: 2016
Authors:
Pizon M, Zimon D, Pachmann U, Pachmann K.
Title:
Frequent expression of PDL-1 on circulating epithelial tumor cells (CETCs) could be a new therapeutic target in breast cancer patients.
Published in Medium:
Oncol Res Treat 2016, 39(suppl1):D0303
Published in the year: 2016
Authors:
Pizon M, Zimon D, Pachmann U, Pachmann K.
Title:
PDL-1 is more frequently expressed on circulating epithelial tumor cells (CETCs) in metastatic breast cancer patients and could be a crucial factor in the inhibition of immune response to CETCs during metastatsis formation.
Published in Medium:
Molecular Cancer Therapeutics 2016, #B95
Published in the year: 2016
Authors:
Zimon D, Pizon M, Mayer V, Pachmann K.
Title:
Stem cell markers are overexpressed in tumorsheres cultured from circulating epithelial tumor cells (CETCs) in patients with breast cancer.
Published in Medium:
Cancer Res 2016, 76:P3-07-59, doi: 10.1158/1538-7445.SABCS 15-P3-07-59
Published in the year: 2015
Authors:
Zimon D, Pizon M, Maier V, Pachmann U, Pachmann K.
Title:
Tumorsphären, die aus CETCs von Patienten mit soliden Tumoren kultiviert wurden, zeigen eine überexpression von Stammzellmarkern.
Published in Medium:
Oncol Res Treatment 2015, 38 (suppl 5): 1-288 (P-502)
Published in the year: 2015
Authors:
Pizon M, Zimon D, Pachmann U, Pachmann K.
Title:
Die Anzahl der aus CECTs kultivierten Tumorsphären hängt von dem Stadium der Krankheit und dem Einsatz einer Chemotherapie ab.
Published in Medium:
Oncol Res Treatment 2015, 38 (suppl 5): 1-288 (V-631)
Published in the year: 2015
Authors:
Pizon M, Zimon D, Maier V, Pachmann U, Pachmann K.
Title:
PDL-1 is highly expressed on circulating epithelial tumor cells (CETCs) and could ba a crucial factor in the inhibition of immune response to CETCs during metastasis formation.
Published in Medium:
EJC 2015, 51 (suppl 3): p 18-19
Published in the year: 2015
Authors:
Zimon D, Pizon M, Pachmann U, Pachmann K.
Title:
Characterisation of tumorspheres cultured from circulating epithelial tumor cells (CETCs) in pancreatic cancer patients.
Published in Medium:
EJC 2015, 51 (suppl 3): p6
Published in the year: 2015
Authors:
Zimon D, Pizon M, Stein EL, Pachman UA, Pachmann K.
Title:
Vemurafenib to eliminate BRAF-mutated circulating epithelial tumor cells (CETCs) from blood of patients with malignant melanoma.
Published in Medium:
J Clin Oncol 2015, 33 (suppl; abstr e11031)
Published in the year: 2015
Authors:
Pizon M, Zimon D, Pachmann UA, Pachmann K.
Title:
Tumorspheres cultured from circulating epithelial tumor cells (CETCs) in pancreatic cancer patients having cancer stem cells properties and resistance to standard chemotherapeutics.
Published in Medium:
J Clin Oncol 2015, 33 (suppl; abstr e22031)
Published in the year: 2015
Authors:
Pizon M, Zimon D, Pachmann UA, Pachmann K.
Title:
The number of tumorspheres cultured from CETCs in breast cancer patients in relation to stage of the disease and administration of chemotherapy.
Published in Medium:
J Clin Oncol 2015, 33 (suppl; abstr e22032)
Published in the year: 2015
Authors:
Pachmann K, Schuster, S.
Title:
Brustkrebs-Überwachung nach Ende der Hormontherapie: Bieten zirkulierende epitheliale Tumorzellen eine Entscheidungshilfe?
Published in Medium:
Gyne 2015, 05:28-32
Published in the year: 2015
Authors:
Pachmann K, Schuster S.
Title:
Brustkrebsüberwachung: Bieten zirkulierende epitheliale Tumorzellen eine Entscheidungshilfe?
Published in Medium:
DZKF 2015, 3:15-19
Published in the year: 2015
Authors:
Guntinas-Lichius O, Pachmann K.
Title:
Zirkulierende Tumorzellen bei Kopf-Hals-Tumoren.
Published in Medium:
DOI 10.1055/s-0035-1548921, Laryngo-Rhino-Otol 2015, 94:367-73
Published in the year: 2015
Authors:
Pachmann K.
Title:
Wie beeinflußt die Therapie solider epithelialer Tumore die im Blut zirkulierenden Tumorzellen.
Published in Medium:
DZO 2015, 47:82-87
Published in the year: 2015
Authors:
Pachmann K.
Title:
Current and potential use of MAINTRAC method for cancer diagnosis and Prediction of metastasis.
Published in Medium:
Expert Rev Mol Diagn
Published in the year: 2015
Authors:
Inhestern J, Oertel K, Stemmann V,Schmalenberg H, Dietz A, Rotter N, Veit J, Goerner M, Sudhoffs H, Junghans C, Wittekindt C, Pachmann K, Guntinas-Lichius O.
Title:
Prognostic Role of Circulating Tumor Cells during Induction Chemotherapy Followed by Curative Surgery Combined with Postoperative Radiotherapy in Patients with Locally Advanced Oral and Oropharyngeal Squamous Cell Cancer.
Published in Medium:
PLoS One
Published in the year: 2014
Authors:
Mahal K, Schill E, Breyer S, Pachmann U, Pachmann K, Schobert R, Biersack B.
Title:
Acitivity of a Doxorubicin Menthol Conjugate against Circulating Epithelial Tumor Cells of Cancer Patients.
Published in Medium:
J Pharm Sci Pharmacol 2014, 2:1-4, DOI:10.1166/jpsp.2014.1027
Published in the year: 2014
Authors:
Zimon D, Pizon M, Stein EL, Pachmann U, Pachmann K.
Title:
Differential chemosensitivity between CETCs and tumour spherodis in cancer patients with solid tumors.
Published in Medium:
Europ J Cancer 2014, 50(suppl 6):62, #190
Published in the year: 2014
Authors:
Winkens T, Pachmann K, Fressmeyer M.
Title:
The influence of radioiodine therapy on the number of circulating epitzelial cells (CEC) in patients with differentiated thyroid carcioma - a pilot study.
Published in Medium:
Exp Clin Endocrinol Diabetes 2014, 122: 246-253
Published in the year: 2014
Authors:
Pachmann K, Zimon D, Pizon M, Pachmann U.
Title:
Tumor spheres growing from peripherally circulating tumor cells exhibit stem cell features.
Published in Medium:
Cancer Res December 15, 2013 73:PD6-1; doi:10.1158/0008-5472.SABCS13-PD6-1
Published in the year: 2014
Authors:
Pachmann K.
Title:
Tumorspheres cutured from circulating epithelial tumor cells (CETCs) as diagnostic marker in patients with solid cancers.
Published in Medium:
J Clin Oncol 2014, 32:705, #11043
Published in the year: 2014
Authors:
Pachmann K.
Title:
Comparison of chemosensitivity testing of CETCs and spheroids in cancer patients with solid tumors.
Published in Medium:
J Clin Oncol 2014, 32:166, #2598
Published in the year: 2014
Authors:
Pachmann K, Pizon M, Zimon D, Stein EL.
Title:
Somatic mutations of the EGFR, KRAS and BRAF genes: Heterogeneity in circulating epithelial tumor cells (CETC) as determined using the Cobas Z480 analyzer.
Published in Medium:
Europ J Cancer 2013, 49(suppl.4):34(#MC13-0080)
Published in the year: 2014
Authors:
Zimon D, Pizon M, Pachmann U, Pachmann, Pachmann K.
Title:
Determining the role of IGF-IR and VEGFR-2 in the development of resistance to trastuzumab in breast cancer.
Published in Medium:
Oncol Res Treat 2014, 37 (suppl 5):262(#P798)
Published in the year: 2014
Authors:
Pizon M, Zimon D, Pachmann U, Pachmann, Pachmann K
Title:
In vitro chemosensitivity testing of spheroids cultured from CETCs of cancer patients with solid tumors.
Published in Medium:
Oncol Res Treat 2014, 37 (suppl 5):271(#P822)
Published in the year: 2014
Authors:
Zuerch M, Foertsch S, Matzas M, Pachmann K, Kuth R.
Title:
Cancer cell classification with coherent diffraction imaging using an extreme ultraviolet radiation source.
Published in Medium:
J. Med. Imag. 1(3), 031008 (Oct 03, 2014). doi:10.1117/1.JMI.1.3.031008
Published in the year: 2014
Authors:
Sorg S, Pachmann K, Brede-Hekimian K, Freesmeyer M, Winkens T.
Title:
Determining tissue origin of circulating epithelial cells (CEC) in patients with differentiated thyroid cancer by real-time PCR using thyroid mRNA probes.
Published in Medium:
Cancer Letters. dx.doi.org./10.1016/j.canlet.2014.09.046
Published in the year: 2014
Authors:
D. Zimon, M. Pizon, U. Pachmann, K. Pachmann
Title:
A SUBPOPULATION AMONG CIRCULATING EPITHELIAL TUMOR CELLS IN PATIENTS WITH SOLID CANCER IS CAPABLE OF SPHERE FORMATION AND CARRIES CANCER STEM CELL PROPERTIES
Published in Medium:
Poster Abstracts - IFCC WorldLab Istanbul 2014 - Istanbul, 22-26 June 2014 - DOI 10.1515/cclm-2014-4013 Clin Chem Lab Med 2014; 52, Special Suppl, pp S1 - S1760, June 2014 - Copyright by Walter de Gruyter - Berlin - Boston S436
Published in the year: 2014
Authors:
D. Zimon, M. Pizon, U. Pachmann, K. Pachmann
Title:
EGFR, KRAS AND BRAF MUTATION ANALYSIS IN INDIVIDUALLY DEPOSITED SINGLE CIRCULATING EPITHELIAL TUMOR CELLS (CETCS) USING THE COBAS Z 480 ANALYZER
Published in Medium:
Poster Abstracts - IFCC WorldLab Istanbul 2014 - Istanbul, 22-26 June 2014 - DOI 10.1515/cclm-2014-4013 Clin Chem Lab Med 2014; 52, Special Suppl, pp S1 - S1760, June 2014 - Copyright by Walter de Gruyter - Berlin - Boston S387
Published in the year: 2013
Authors:
Ernst Ludwig Stein, Dagmar Samsel, Ulrich Pachmann
Title:
Relative Stoichiometry and Affinity for Describing Von Willebrand Factor Binding of Coagulation Factor VIII
Published in Medium:
WebmedCentral HAEMOTOLOGY
Published in the year: 2013
Authors:
S. Schuster, K. Pachmann
Title:
Zirkulierende Tumorzellen - Potenzielle diagnostische Marker und prognostische Faktoren
Published in Medium:
Deutsche Apotheker Zeitung Nr. 48, 28.11.2013, 153. Jahrgang
Published in the year: 2013
Authors:
Zimon D, Pizon M, Pachmann U, Pachmann K.
Title:
Insulin like growth factor receptor-1 (IGF-IR) and vascular endothelial growth fractor receptor 2 (VEGFR-2) are detectable on circulating epithelial tumor cells (CETCs) in patients with solid tumors.
Published in Medium:
Onkologie 2013, 36(suppl 7): 269 #P874
Published in the year: 2013
Authors:
M. Pizon, D. Zimon, S. Carl, U. Pachmann, K. Pachmann and O. Camara
Title:
Heterogeneity of circulating epithelial tumour cells from individual patients with respect to expression profiles and clonal growth (sphere formation) in breast cancer
Published in Medium:
ecancer medicalscience
Published in the year: 2013
Authors:
Rüdiger N, Stein EL, Schill E, Spitz G, Rabenstein C, Stauch M, Rengsberger M, Runnebaum IB, Pachmann U, Pachmann K.
Title:
Chemosensitivity Testing of Circulating Epithelial Tumor Cells (CETC) in Vitro: Correlation to in Vivo Sensitivity and Clinical Outcome.
Published in Medium:
J Cancer Therapy 2013, 4:597-605
Published in the year: 2013
Authors:
Pizon M, Zimon DS, Pachmann U, Pachmann K.
Title:
Insulin-Like Growth Factor Receptor I (IGF-IR) and Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) Are Expressed on the Circulating Epithelial Tumor Cells of Breast Cancer Patients.
Published in Medium:
PLoS ONE 2013, 8(2): e56836. doi:10.1371/journal.pone.0056836
Published in the year: 2012
Authors:
Retsky M, Rogers R, Demicheli R, Hrushesky WJM, Gukas I, Vaidya JS, Baum B, Forget P, DeKock M, Pachmann K.
Title:
NSAID analgesic ketorolac used peroperatively may suppress early breast cancer relapse: particular relevance to triple negative subgroup
Published in Medium:
Breast Cancer Res Treat 2012, DOI: 10.1007/s10549-012-2094-5
Published in the year: 2012
Authors:
Hekimian K, Meisezahl S, Trompelt K, Rabenstein C, Pachmann K
Title:
Epithelial Cell Dissemination and Readhesion: Analysis of Factors Contributing to Metastasis Formation in Breast Cancer
Published in Medium:
ISRN Oncology Volume 2012, Article ID 601810, 8 pages doi:10.5402/2012/601810
Published in the year: 2011
Authors:
Hekimian K, Stein EL, Pachmann U, Pachmann K
Title:
Demasking of epithelial cell adhesion molecule (EpCAM) on circulating epithelial tumor cells by Tween(
Published in Medium:
Clin Chem Lab Med 2011, DOI 10.1515/CCLM.2011.812
Published in the year: 2011
Authors:
Hoemberg M, Stahl D, Schlenke P, Sibrowski W, Pachmann U, Cassenes U
Title:
The Isotype of Autoantibodies influences the Phagocytosis of Antibody-Coated Platelets in Autoimmune Thrombocytopenic Purpura
Published in Medium:
Scand J Immunol 2011, 74:489-495
Published in the year: 2011
Authors:
Pachmann K
Title:
Nicht verwunderlich
Published in Medium:
Leserbrief zu D433/2011: Nachweis zirkulierender Tumorzellen: Nicht für die Routine reif von Vera Zylka-Menhorn. Deutsches Ärzteblatt 2011, 41:A2158
Published in the year: 2011
Authors:
Stein EL, Pachmann U
Title:
Von Willebrand faktor binding factor VIII: a new method to determine relative stoichiometry and affinity
Published in Medium:
Transfus Med Hemother 2011, 38 (suppl 1):72 #OS9.4
Published in the year: 2011
Authors:
Pachmann K, Camara O, Kroll T, Gajda M, Gellner AK, Wotschadlo J, Runnebaum IB
Title:
Efficacy control of Therapy Using Circulating Epithelial Tumor Cells (CETC) as "Liquid Biopsy": Trastuzumab in HER2/neu-Positive Breast Carcinoma
Published in Medium:
J Cancer Res Clin Oncol 2011, 137: 1317-1327, DOI: 10.1007/s00432-011-1000-6
Published in the year: 2011
Authors:
Pachmann K
Title:
Tumor cell seeding during surgery - possible contribution to metastasis formation
Published in Medium:
Cancers 2011, 3: 2540-2553; doi:10 3390/cancers3022540
Published in the year: 2011
Authors:
Pizon MT, Pizon M, Friedel N, Pachmann U
Title:
Acute Multi Thrombotic Stroke as Clinical Manifestation of Heparin induced Thrombocytopenia (HIT) in a patient following cardiac surgery
Published in Medium:
Clin Chem Lab Med 2011, 92 (special Suppl): S? #0271
Published in the year: 2011
Authors:
Pizon M, Pachmann U, Schill E, Spitz G, Pachmann K
Title:
Chemosensitivity of circulating epithelial tumor cells (CETC) does not change under the influence of cryopreservation
Published in Medium:
Clin Chem Lab Med 2011, 92 (special Suppl): S222 #0059
Published in the year: 2011
Authors:
Pachmann U, Hekimian K, Carl S, Ruediger N, Rabenstein C, Pachmann K
Title:
Comparing Sequential Steps For Detection Of Circulating Tumor Cells: More Specific Or Just Less Sensitive?
Published in Medium:
WebmedCentral CANCER 2011;2(2):WMC001490
Published in the year: 2011
Authors:
Pachmann K Camara O, Kohlhase A, Rabenstein C, Kroll T, Runnebaum IB, Hoeffken K
Title:
Assessing the efficacy of targeted therapy using circulating epithelial tumor cells (CETC:): the example of SERM therapy monitoring as a unique tool to individualize therapy
Published in Medium:
J Cancer Res Clin Oncol 2011, 137:821-828, doi: 101007/s00432-010-0942-4
Published in the year: 2010
Authors:
Carl S, Camara O, Plaschke-Schluetter A, Kroll T, Pachmann K
Title:
Molecular Analysis of Single Circulating Tumor Cells for Characterization of the Targets of Systemic Breast Cancer Therapy as Chance to Individualize Therapy
Published in Medium:
Cancer Res 2010, 70(24 Suppl):274s (P3-10-37)
Published in the year: 2010
Authors:
Hekimian K, Camara O, Kroll T, Joerke C, Krauspe S, Pachmann K, Runnebaum I
Title:
The impact of trastuzumab on the course of disease in HER2/neu positive breast cancer
Published in Medium:
Archives of Gynecology and Obstetrics 2010, 282(Suppl 1): S48 (FV-Onko 03 17)
Published in the year: 2010
Authors:
Pachmann K, Kroll T, R
Title:
Detection and molecular characterization of circulating epithelial tumor cells from solid tumors: A comparison of two methods
Published in Medium:
Onkologie 2010, 33(suppl 6):53-4 (P192)
Published in the year: 2009
Authors:
Pachmann K, Camara O, Rabenstein C, Winzer H, Runnebaum IB
Title:
Circulating Epithelial Tumor Cell (CETC) Monitoring during SERM and Aromatase Inhibitor Treatment for Early Detection of Patients Resistant to Tamoxifen
Published in Medium:
Cancer Res 2009, 69(Suppl):808s (#5129)
Published in the year: 2009
Authors:
Camara O, Kroll T, Oppel S, Runnebaum IB, Pachmann K
Title:
Circulating Epithelial Cells as a Tool for Monitoring Treatment Success of Primary Chemotherapy with Simultaneous or Sequential and without Trastuzumab
Published in Medium:
Cancer Res 2009, 69(Suppl):651s (#3016)
Published in the year: 2009
Authors:
Hammer U, Camara O, Hekimian K, Gellner AK, Runnebaum IB, Pachmann K
Title:
Changing Therapy as a Consequence of the Behaviour of CETC during Adjuvant Trastuzumab Treatment in Patients with Her2/Neu Positive Breast Cancer
Published in Medium:
Cancer Res 2009, 69(Suppl):612s (#2088)
Published in the year: 2009
Authors:
Pachmann K, Stein EL, Schill E, Pachmann U
Title:
Chemosensitivity Testing of Circulating Epithelial Cells (CETC) in Breast Cancer Patients and Correlation to Clinical Outcome
Published in Medium:
Cancer Res 2009, 69(Suppl):606s (#2044)
Published in the year: 2009
Authors:
Pachmann K, Camara O, Runnebaum IB, Hoeffken K
Title:
Gauging the response of circulating epithelial tumor cells (CETC) an tumor stem cell subpopulation to therapy of early-stage
Published in Medium:
J Clin Oncol 2009, 27(S15):564 #11026
Published in the year: 2009
Authors:
Hekimian K, Stein EL, Pachmann U, Pachmann K
Title:
Detection of tumor stem cells among circulating epithelial tumor cells (CETC) and relationship to therapy response
Published in Medium:
Cancer Res 2009, 69(Suppl):324s (#5053)
Published in the year: 2009
Authors:
Pachmann K, Camara O, Gajda M, Rabenstein C, Pachmann U, Runnebaum IB
Title:
Metastatic potential of Her2/neu positive and Her2/neu negative circulating epithelial tumor cells (CETC) released during primary systemic chemotherapy
Published in Medium:
Cancer Res 2009, 69(Suppl):317s-318s (#5031)
Published in the year: 2009
Authors:
Camara O, Hammer U, Gajda M, Kroll T, Krauspe S, Gellner A-K, Joerke C, Runnebaum IB, Hoeffken K, Pachmann K
Title:
Behaviour and metastatic potential of her2/neu positive and her2/neu negative circulating epithelial tumor cells (CETC) during adjuvant systemic therapy in breast cancer
Published in Medium:
Cancer Res 2009, 69(Suppl):317s(#5030)
Published in the year: 2009
Authors:
Camara O, J
Title:
Monitoring circulating epithelial tumour cells (CETC) to gauge therapy: in patients with disease progression after trastuzumab persisting CETC can be eliminated by combined lapatinib treatment
Published in Medium:
J Cancer Res Clin Oncol 2009, 135:643-7
Published in the year: 2008
Authors:
Gajda M, Camara O, Oppel S, Kroll T, J
Title:
Monitoring circulating epithelial tumor cells (CETC) during primary systemic chemotherapy including trastuzumab for early prediction of outcome in patients with Her2/neu-positive tumors
Published in Medium:
Ann Oncol 2008, 19:2090-1
Published in the year: 2008
Authors:
Pachmann K
Title:
Circulating Tumor Cells in Breast Cancer: Ficition or Reality?
Published in Medium:
J Clin Oncol 2008, 26:3656-3657
Published in the year: 2008
Authors:
Pachmann K, Camara O, Gajda M, Untch M, Hoeffken K
Title:
The initial response of circulating epithelial tumor cells (CETC) during primary systemic therapy of breast cancer is predictive for early relapse
Published in Medium:
Ann Oncol 2008, 19(suppl5):136 (#24PD)
Published in the year: 2008
Authors:
Pachmann K, Camara C, Hammer U, Joerke C, Krauspe S, Rabenstein C, Runnebaum IB, Hoeffken K
Title:
The impact of systemic chemotherapy on circulating epithelial tumor cells (CETC) in breast cancer
Published in Medium:
J Clin Oncol 2008, 26 (suppl):578s (#11001)
Published in the year: 2008
Authors:
Pachmann K, Stein EL, Rabenstein C, Clement HJ, Pachmann U
Title:
Targeting circulating epithelial tumor cells (CETC) to assess the effectivity and mode of action of new cytotoxic agents in breast cancer
Published in Medium:
Proceedings Supplement: Late-Breaking Abstracts 2008, #LB-183, p51-52
Published in the year: 2008
Authors:
Pachmann K, Dengler R Lobodasch K, Fr
Title:
An increase in cell number at completition of therapy may develop as an indicator of early relapse Quantification of circulating tumor cells (CETC) for monitoring of adjuvant therapy in breast cancer
Published in Medium:
J Cancer Res Clin Oncol 2008, 134:59-65
Published in the year: 2008
Authors:
Pachmann K, Camara O, Kavallaris A, Krauspe S, Malarski N, Gajda M, Kroll T, J
Title:
Monitoring the Response of Circulating Epithelial Tumor Cells (CETC) to Adjuvant Chemotherapy in Breast Cancer Allows Detection of Patients at Risk of Early Relapse
Published in Medium:
J Clin Oncol 2008, 26 (8): 1208-1215
Published in the year: 2007
Authors:
Camara O, Kavallaris A, Rengsberger M, Koch A, Schneider U, Egbe A, Untch M, Pachmann K
Title:
The initial response of circulating epithelial tumor cells to primary systemic chemotherapy in breast cancer is highly predictive for final tumor reduction an outcome
Published in Medium:
Breast Cancer Research and Treatment 2007, 106 (Suppl 1):A4019, P172
Published in the year: 2007
Authors:
Pachmann K, Camara O, Kavallaris A, Krauspe S, Malarski N, Gajda M, Kroll, T, Runnebaum I, Hoeffken K
Title:
Circulating epithelial tumor cells a new tool for therapy monitoring in breast cancer: a more than tenfold increase in numbers during systemic therapy is highly predictive of relapse
Published in Medium:
Breast Cancer Research and Treatment 2007, 106 (Suppl 1):A110, P26
Published in the year: 2007
Authors:
Pachmann K, Camara O, Kavallaris A, Lobodasch K, Rengsburger M, Koch A, Kroll T, Sch
Title:
Die Bedeutung zirkulierender epithelialer Tumorzellen (CETC) für die Therapieüberwachung in der neoadjuvanten und der adjuvanten Therapie des Mammakarzinoms.
Published in Medium:
Senologie 2007, 4:A87, P129
Published in the year: 2007
Authors:
Camara O, Rengsberger M, Egbe A, Koch A, Gajda M, Hammer U, J
Title:
The Relevance of Circulating Epithelial Tumour Cells (CETC) for Therapy Monitoring during Neoadjuvant (Primary Systemic) Chemotherapy in Breast Cancer
Published in Medium:
Annals of Oncology 2007, 18:1484-1492
Published in the year: 2007
Authors:
Lobodasch K, Fr
Title:
Quantification of circulating tumour cells for monitoring of adjuvant therapy in breast cancer: An increase in cell number at completion of therapy is a predictor of early relapse
Published in Medium:
The Breast 2007, 16:211-218
Published in the year: 2006
Authors:
Kohlhase A, Malarski N, Camara O, Krauspe S, Runnebaum I, Hoeffken K, Pachmann K
Title:
Circulating tumor cells, tools for monitoring and targets for therapy
Published in Medium:
Onkologie 2006, 29(s3):129, Abstract#601
Published in the year: 2006
Authors:
Pachmann K, Clement JH, Hoeffken K, Camara O, Schneider CP, Pachmann U
Title:
The hidden face of tumor treatment: tumor cell dissemination during treatment steps counteracts treatment success
Published in Medium:
Proc Amer Assoc Cancer Res, 2006, 47:Abstract#1968
Published in the year: 2006
Authors:
Günther J, Waldau A, Hoeffken K, Pachmann K.
Title:
Longitudinal analysis of bone marrow infiltration in acute lymphatic leukemia during therapy: early detection of imminent relapse
Published in Medium:
Onkologie 2006, 29(s3): 78, P433
Published in the year: 2006
Authors:
Pachmann K
Title:
Release of tumor cells during neoadjuvant therapie
Published in Medium:
Breast-Cancer-Research, Nov 1, 2006, Leserbrief zu: Breast Cancer Research 2006, 8:R60
Published in the year: 2006
Authors:
Camara O, Kavallaris A, N
Title:
Seeding of epithelial cells into circulation during surgery for breast cancer: the fate of malignant and benign mobilized cells
Published in Medium:
World Journal of Surgical Oncology 2006, 4:67
Published in the year: 2006
Authors:
Schwalbe M, Pachmann K, H
Title:
Improvement of the separation of tumour cells from peripheral blood cells using magnetic nanoparticles
Published in Medium:
J Phys Condens Matter 2006, 18:1-12
Published in the year: 2006
Authors:
Clement JH, Schwalbe M, Buske N, Wagner K, Schnabelrauch M, G
Title:
Differential interaction of magnetic nanoparticles with tumor cells and peripheral blood cells
Published in Medium:
J Cancer Res Clin Oncol 2006, 132:287-292
Published in the year: 2006
Authors:
Schwalbe M, Buske N, Vetterlein M, H
Title:
The Carboxymethyl Dextran Shell is an Important Modulator of Magnetic Nanoparticle Uptake in Human Cells
Published in Medium:
Z Phys Chem 2006, 220:125-131
Published in the year: 2006
Authors:
Stahl D, Hoemberg M, Cassens U, Pachmann U, Sibrowski W
Title:
Influence of isotypes of disease-associated autoantibodies on the expression of natural autoantibody repertoires in humans
Published in Medium:
Immunology Letters 2006, 102:50-59
Published in the year: 2006
Authors:
Pachmann K, Camara O, Lobodasch K, Dengler R, Runnebaum I, Hoeffken K, Pachmann U
Title:
Circulating tumor cells, tools for monitoring and targets for therapy
Published in Medium:
Journal of Clinical Oncology 2006, 24(18S):32, Abstract#617
Published in the year: 2005
Authors:
Schwalbe M, Järke C, Buske N, Häffken K, Pachmann K, Clement JH.
Title:
Selective reduction of the interaction of magnetic nanoparticles with leucocytes and tumor cells by human plasma
Published in Medium:
Journal of Magnetism and Magnetic Materials 2005, 293:433-437
Published in the year: 2005
Authors:
Pachmann K, Camara O, Kavallaris A, Schneider U, Schünemann S, Häffken K.
Title:
Quantification of the Response of Circulating Epithelial Cells (CEC) to Neodadjuvant Treatment of Breast Cancer: A New Tool for Therapy Monitoring
Published in Medium:
Breast Cancer Research 2005, 7:R975-R979
Published in the year: 2005
Authors:
Rolle A, Günzel R, Pachmann U, Willen B, Häffken K, Pachmann K.
Title:
Increase in number of circulating disseminated ephitelial cells after sugery for non-small cell lung cancer monitoring by MAINTRAC is a predictor for relapse: A preliminary report
Published in Medium:
World Journal surgical Oncology 2005, 3:18
Published in the year: 2005
Authors:
Hümmer H, Pachmann K, Pachmann U.
Title:
Adjuvante homöopathische Therapie bei konventionell behandeltem Mammakarzinom
Published in Medium:
AHZ 2005, 250:127-133
Published in the year: 2005
Authors:
Pachmann K
Title:
Longtime Recirculating Tumor Cells in Breast Cancer Patients
Published in Medium:
Clinical Cancer Research 2005, 11:5657-5658
Published in the year: 2005
Authors:
Carlson RH
Title:
Finding& Identifying Disseminated Tumor Cells as Biomarkers for Solid Cancers
Published in Medium:
Oncology Times 2005, XXVII(11):10-11
Published in the year: 2005
Authors:
Pachmann K, Clement JH, Schneider CP, Willen B, Camara O, Pachmann U, Häffken K.
Title:
Standardized quantification of circulating peripheral tumor cells from lung and breast cancer
Published in Medium:
Clin Chem Lab Med 2005; 43:617-627
Published in the year: 2005
Authors:
Pachmann K, Clement JH, Hoeffken K, Schneider CP, Lobodasch K, Camara O,Pachmann U
Title:
Quantitative monitoring of circulating epithelial cells for individal therapy control in lung and breast cancer during neoadjuvant treatment, surgery and adjuvant chemotherapy
Published in Medium:
Journal of Clinical Oncology 2005, 23(16S):36s, Abstract#631
Published in the year: 2005
Authors:
Pachmann K
Title:
Neoadjuvant Chemotherapy for Breast Cancer Can Cause Release of Tumor Cells
Published in Medium:
Oncology News International, 2005, 03:29
Published in the year: 2004
Authors:
Wagner K, Kautz A, Räder M, Schwalbe M, Pachmann K, Clement JH, Schnabelrauch M.
Title:
Synthesis of oligonucleotide-functionalized magnetic nanoparticles and study on their invitro cell uptakte
Published in Medium:
Appl Organometal Chem 2004, 18:514-519
Published in the year: 2004
Authors:
Schwalbe M, Järke C, Hausschild F, Häffken K, Pachmann K, Clement JH.
Title:
Human Plasma Facilitates Enrichment of Circulating Epithelial Cells from Peripheral Blood
Published in Medium:
Onkologie 2004, 27(S3):142, P630
Published in the year: 2004
Authors:
Schwalbe M, Hausschild F, Pachmann K, Clement JK
Title:
Human plasma increases the magnetic separation of tumor cells from peripheral blood leukocytes
Published in Medium:
5th Colloquium DFG-Priority Program "Kolloidale magnetische Fl
Published in the year: 2004
Authors:
Pachmann K, Camara O
Title:
Influence of Neoadjuvant Therapy in Breast Cancer on Circulating Tumor Cells
Published in Medium:
95th Annual Meeting of the American Association for Cancer Research March 27-31, 2004, p94, Abstract#LB-161
Published in the year: 2004
Authors:
Pachmann K, Camara O, Pachmann U
Title:
Influence of primary tumor chemotherapy in breast cancer on circulating tumor cells Indications for massive cell release into circulations concurrent with tumor size reduction
Published in Medium:
Breast Cancer Research and Treatment 2004, 88:224, Abstract#6014
Published in the year: 2004
Authors:
Pachmann K, Tulusan AH, Lobodasch K, Dengler R, Pachmann M, Pachmann U
Title:
Monitoring the efficacy of adjuvant therapy in breast cancer by quantifying circulating tumor cells using the MAINTRAC analysis (Laser scanning cytometry of magnetic bead enrichtment cells)
Published in Medium:
7th Congress of European Society for Analytical Cellular Pathology 2001, Abstract P6
Published in the year: 2003
Authors:
Pachmann K, Clement J, H
Title:
An approach to standardize the detection circulating tumor cells comparing different methods for analysis in peripheral blood and bone marrow
Published in Medium:
Onkologie 2003, 26(S5):191, P932
Published in the year: 2001
Authors:
Pachmann K
Title:
Nachweis minimaler zirkulierender Tumorzellen mit Hilfe mikroflourimetrischer Analysen am Laser Scanning Cytometer (LSC)
Published in Medium:
Innovationsforum 04-5 September 2001, 18-19
Published in the year: 2001
Authors:
Pachmann K, Heiss P, Demel U, Tilz G
Title:
Detection and quantification of small numbers of circulating tumour cells in peripheral blood using laser scanning cytometer (LSC
Published in Medium:
Clin Chem Lab Med 2001, 39:811-817
Published in the year: 2001
Authors:
Pachmann K, Lychatz S, Oblonczek G, Willen B
Title:
Tumorzell-Analyse mit kombinierter Magnetanreicherung, Laser-Scanning-Zytometrie und visueller Kontrolle
Published in Medium:
LABORWELT 2001, IV:23-26
Published in the year: 2001
Authors:
Pachmann K, Zhao S, Schenk T, Kantarjian H, El-Naggar AK, Siciliano MJ, Guo JQ, Arlinghaus RB, Andreff M
Title:
Expression of bcr-abl mRNA in individual chronic myelogenous leukaemia Cells as determined by in situ amplification
Published in Medium:
British Journal of Haematology 2001, 112:749-759
Published in the year: 2000
Authors:
Eichler P, Barthels K, Budde U, Haas S, Kroll H, Loreth M, Pachmann U, P
Title:
Workshop on the validation of the Heparin-Induced-Platelet-Activation-Assay (HIPA)
Published in Medium:
Annals of Haematology 1997, 74:
Published in the year: 2000
Authors:
Tilz GP, Pachmann K, Demel U
Title:
LSC - Laser Scanning cytometry as an application for the detection of tumor cells in the peripheral blood
Published in Medium:
An experimental study Onkologie 2000, 23(S7): Abstract#:0215
Published in the year: 2000
Authors:
Pachmann K, Pachmann U
Title:
Minimale residuale Tumorerkrankung bei soliden epithelialen Tumoren
Published in Medium:
Leserbrief: Neues automatisiertes Analyseverfahren Deutsches
Published in the year: 2000
Authors:
Pachmann K, Pachmann U
Title:
MAINTRAC Approach For Detection Of Circulating Tumour Cells: Sensitivity, Specificity, Reproducibility
Published in Medium:
Vox Sanguinis 2000, 78 (suppl 1), Poster#615
Published in the year: 2000
Authors:
Pachmann U
Title:
HIPA Test: Improved sensitivity and specifity
Published in Medium:
Vox Sanguinis 2000, 78 (suppl 1), Poster#054
Published in the year: 2000
Authors:
Jungwirth-Schill C, Pachmann U, Pachmann K
Title:
Antibodies against carbohydrate targets on GPIB/V/IX complex in Thrombocytopenic patients as detected by MAIPA
Published in Medium:
Vox Sanguinis 2000, 78 (suppl 1), Poster#063
Published in the year: 2000
Authors:
Pachmann U, Jungwirth-Schill C, Stein EL
Title:
Transfusion Medical Pharmacology: abcixmab selectively interferes with binding of human anti platelet auto- and alloantibodies to GPIIb/IIIa as monitored by PSIFT and MAIPA
Published in Medium:
Vox Sanguinis 2000, 78 (suppl 1), Poster#064
Published in the year: 2000
Authors:
Pachmann K, Pachmann U
Title:
Laser scanning cytometry and magnet bead enrichment for rapid quantitative enumeration of minimal Numbers of tumor cells in peripheral blood and bone marrow in breast cancer patients
Published in Medium:
Journal of Clinical Oncology 2000, 18:Abstract# 541
Published in the year: 2000
Authors:
Pachmann K, Tolkmitt M, Mengel M, Rinas N, Dressel V, Lobodasch K, Tulusan AH, Pachmann U
Title:
Real time monitoring the efficacy of adjuvant therapy in breast cancer by quantifying the reduction of circulating tumor cells using the MAINTRAC analysis
Published in Medium:
Breast Cancer Research and Treatment 2000, 64:#402